{
  "url": "https://openlegislation.uk/eu-regulation-2019-521/annex-IV",
  "json_url": "https://openlegislation.uk/eu-regulation-2019-521/annex-IV.json",
  "legislation": "eur/2019/521",
  "legislation_title": "Commission Regulation (EU) 2019/521 of 27 March 2019 amending, for the purposes of its adaptation to technical and scientific progress Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures (Text with EEA relevance)",
  "legislation_url": "https://openlegislation.uk/eu-regulation-2019-521",
  "path": "annex/IV",
  "kind": "annex",
  "number": "IV",
  "heading": null,
  "text": "Annex IV to Regulation (EC) No 1272/2008 is amended as follows:\n(1) The first introductory paragraph of Annex IV is replaced by the following:\n‘This Annex sets out a matrix listing the recommended precautionary statements for each hazard class and hazard category by type of precautionary statement. The matrix guides the selection of appropriate precautionary statements, and includes elements for all categories of precautionary action. All specific elements relating to particular hazard classes shall be used. In addition, general precautionary statements not linked to a certain hazard class or category shall also be used where relevant.\nTo provide flexibility in the application of precautionary phrases, combinations or consolidations of precautionary statements are encouraged to save label space and improve readability. The matrix and the Tables in Part 1 of this Annex include a number of combined precautionary statements. However, these are only examples and suppliers may further combine and consolidate phrases where this contributes to clarity and comprehensibility of label information in accordance with Articles 22 and 28(3).\nNotwithstanding Article 22 the precautionary statements that appear on labels or in safety data sheets may incorporate minor textual variations from those set out in this Annex where these variations assist in communicating safety information and the safety advice is not diluted or compromised. These may include spelling variations, synonyms or other equivalent terms appropriate to the region where the product is supplied and used.’\n(2) Table 6.1 is amended as follows:\nThe entry concerning code P103 is replaced by the following:\n‘\nP103\nRead carefully and follow all instructions.\nas appropriate\nConsumer products – omit where P202 is used\n’\n(3) Table 6.2 is amended as follows:\n(a) The entries concerning codes P201 and P202 are replaced by the following:\n‘\nP201\nObtain special instructions before use.\nExplosives (section 2.1)\nUnstable explosive\nGerm cell mutagenicity (section 3.5)\n1A,1B, 2\nConsumer products – omit where P202 is used\nCarcinogenicity (section 3.6)\n1A,1B, 2\nReproductive toxicity (section 3.7)\n1A,1B, 2\nReproductive toxicity — effects on or via lactation (section 3.7)\nAdditional category\nP202\nDo not handle until all safety precautions have been read and understood.\nFlammable gases (section 2.2)\nA, B (chemically unstable gases)\nGerm cell mutagenicity (section 3.5)\n1A,1B, 2\nCarcinogenicity (section 3.6)\n1A,1B, 2\nReproductive toxicity (section 3.7)\n1A,1B, 2\nReproductive toxicity, effects on or via lactation (section 3.7)\nAdditional category\n’\n(b) The entry concerning code P210 is replaced by the following:\n‘\nP210\nKeep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.\nExplosives (section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.4, 1.5\nFlammable gases (section 2.2)\n1A, 1B, 2\nAerosols (section 2.3)\n1, 2, 3\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\n’\n(c) The entry concerning code P212 is inserted:\n‘\nP212\nAvoid heating under confinement or reduction of the desensitising agent.\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\n’\n(d) The entry concerning code P222 is replaced by the following:\n‘\nP222\nDo not allow contact with air.\nFlammable gases (section 2.2)\nPyrophoric gas\nif emphasis of the hazard statement is deemed necessary.\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\n’\n(e) The entry concerning code P230 is replaced by the following:\n‘\nP230\nKeep wetted with …\nExplosives (section 2.1)\nDivisions 1.1, 1.2, 1.3, 1.5\nManufacturer/supplier to specify appropriate material\nfor substances and mixtures which are wetted, diluted, dissolved or suspended with a phlegmatiser in order to suppress their explosive properties\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nManufacturer/supplier to specify appropriate material\n’\n(f) The entry concerning code P233 is replaced by the following:\n‘\nP233\nKeep container tightly closed.\nFlammable liquids (section 2.6)\n1, 2, 3\nif the liquid is volatile and may generate an explosive atmosphere\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nif the chemical is volatile and may generate a hazardous atmosphere\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\n’\n(g) The entry concerning code P280 is replaced by the following:\n‘\nP280\nWear protective gloves/protective clothing/eye protection/face protection/hearing protection/…\nExplosives (section 2.1)\nUnstable explosive and divisions 1.1, 1.2, 1.3, 1.4, 1.5\nManufacturer/supplier to specify the appropriate type of personal protective equipment.\nFlammable gases (section 2.2)\nPyrophoric gas\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSelf-heating substances and mixtures (section 2.11)\n1, 2\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidizing liquids (section 2.13)\n1, 2, 3\nOxidizing solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nSpecify protective gloves/clothing.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin corrosion (section 3.2)\n1A, 1B, 1C\nSpecify protective gloves/clothing and eye/face protection.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin irritation (section 3.2)\n2\nSpecify protective gloves.\nManufacturer/supplier may further specify type of equipment where appropriate.\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nSerious eye damage (section 3.3)\n1\nSpecify eye/face protection.\nManufacturer/supplier may further specify type of equipment where appropriate.\nEye irritation (section 3.3)\n2\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nManufacturer/supplier to specify the appropriate type of personal protective equipment.\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\n’\n(4) Table 6.3 is amended as follows:\n(a) The entries concerning codes P301 and P302 are replaced by the following:\n‘\nP301\nIF SWALLOWED:\nAcute toxicity – oral (section 3.1)\n1, 2, 3, 4\nSkin corrosion (section 3.2)\n1, 1A, 1B, 1C\nAspiration Hazard (section 3.10)\n1\nP302\nIF ON SKIN:\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nSkin irritation (section 3.2)\n2\nSkin sensitisation (section 3.4)\n1, 1A, 1B\n’\n(b) The entry concerning code P332 is replaced by the following:\n‘\nP332\nIf skin irritation occurs:\nSkin irritation (section 3.2)\n2\nmay be omitted if P333 is given on the label.\n’\n(c) The entry concerning codes P370 and P371 are replaced by the following:\n‘\nP370\nIn case of fire:\nExplosives (section 2.1)\nUnstable explosives and divisions 1.1, 1.2, 1.3, 1.4, 1.5\nOxidising gases (section 2.4)\n1\nFlammable liquids (section 2.6)\n1, 2, 3\nFlammable solids (section 2.7)\n1, 2\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nPyrophoric liquids (section 2.9)\n1\nPyrophoric solids (section 2.10)\n1\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic Peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3\nP371\nIn case of major fire and large quantities:\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nDesensitised explosives (section 2.17)\n4\n’\n(d) The entry concerning code P375 is replaced by the following:\n‘\nP375\nFight fire remotely due to the risk of explosion.\nExplosives (section 2.1)\nDivision 1.4\nfor explosives of division 1.4 (compatibility group S) in transport packaging.\nSelf-reactive substances and mixtures (section 2.8)\nType B\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nOrganic peroxides (section 2.15)\nType B\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\n’\n(e) The entry concerning code P377 is replaced by the following:\n‘\nP377\nLeaking gas fire: Do not extinguish, unless leak can be stopped safely.\nFlammable gases (section 2.2)\n1A, 1B, 2\n’\n(f) The entry concerning code P380 is replaced by the following:\n‘\nP380\nEvacuate area.\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nOrganic peroxides (section 2.15)\nTypes A, B\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\n’\n(g) The entry concerning code P381 is replaced by the following:\n‘\nP381\nIn case of leakage, eliminate all ignition sources\nFlammable gases (section 2.2)\n1A, 1B, 2\n’\n(h) The entry concerning code P301 + P312 is replaced by the following:\n‘\nP301 + P312\nIF SWALLOWED: Call a POISON CENTER/doctor/… if you feel unwell\nAcute toxicity – oral (section 3.1)\n4\n… Manufacturer/supplier to specify the appropriate source of emergency medical advice\n’\n(i) The entries concerning codes P370 + P380 + P375 and P371 + P380 + P375 are replaced by the following:\n‘\nP370 + P380 + P375\nIn case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.\nExplosives (section 2.1)\nDivision 1.4\nfor explosives of division 1.4 (compatibility group S) in transport packaging\nDesensitised explosives (section 2.17)\n1, 2, 3\nP371 + P380 + P375\nIn case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.\nOxidising liquids (section 2.13)\n1\nOxidising solids (section 2.14)\n1\nDesensitised explosives (section 2.17)\n4\n’\n(5) Table 6.4 is amended as follows:\n(a) The entry concerning code P401 is replaced by the following:\n‘\nP401\nStore in accordance with …\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\n… Manufacturer/supplier to specify local/regional/national/international regulations as applicable.\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\n’\n(b) The entry concerning code P403 is replaced by the following:\n‘\nP403\nStore in a well-ventilated place.\nFlammable gases (section 2.2)\n1A, 1B, 2\nOxidising gases (section 2.4)\n1\nGases under pressure (section 2.5)\nCompressed gas\nLiquefied gas\nRefrigerated liquefied gas\nDissolved gas\nFlammable liquids (section 2.6)\n1, 2, 3\nfor flammable liquids Category 1 and other flammable liquids that are volatile and may generate an explosive atmosphere.\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nexcept for temperature controlled self-reactive substances and mixtures or organic peroxides because condensation and consequent freezing may take place.\nOrganic peroxides (section 2.15)\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nif the substance or mixture is volatile and may generate a hazardous atmosphere.\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\n’\n(6) Table 6.5 is amended as follows:\n(a) The entry concerning code P501 is replaced by the following:\n‘\nP501\nDispose of contents/container to …\nFlammable liquids (section 2.6)\n1, 2, 3\n… in accordance with local/regional/national/international regulation (to be specified).\nManufacturer/supplier to specify whether disposal requirements apply to contents, container or both.\nSelf-reactive substances and mixtures (section 2.8)\nTypes A, B, C, D, E, F\nSubstances and mixtures which, in contact with water, emit flammable gases (section 2.12)\n1, 2, 3\nOxidising liquids (section 2.13)\n1, 2, 3\nOxidising solids (section 2.14)\n1, 2, 3\nOrganic peroxides (section 2.15)\nTypes A, B, C, D, E, F\nDesensitised explosives (section 2.17)\n1, 2, 3, 4\nAcute toxicity – oral (section 3.1)\n1, 2, 3, 4\nAcute toxicity – dermal (section 3.1)\n1, 2, 3, 4\nAcute toxicity – inhalation (section 3.1)\n1, 2, 3\nSkin corrosion (section 3.2)\n1, 1A, 1B, 1C\nRespiratory sensitisation (section 3.4)\n1, 1A, 1B\nSkin sensitisation (section 3.4)\n1, 1A, 1B\nGerm cell mutagenicity (section 3.5)\n1A, 1B, 2\nCarcinogenicity (section 3.6)\n1A, 1B, 2\nReproductive toxicity (section 3.7)\n1A, 1B, 2\nSpecific target organ toxicity – single exposure (section 3.8)\n1, 2\nSpecific target organ toxicity – single exposure; respiratory tract irritation (section 3.8)\n3\nSpecific target organ toxicity – single exposure; narcotic effects (section 3.8)\n3\nSpecific target organ toxicity – repeated exposure (section 3.9)\n1, 2\nAspiration hazard (section 3.10)\n1\nHazardous to the aquatic environment – acute aquatic hazard (section 4.1)\n1\nHazardous to the aquatic environment – chronic aquatic hazard (section 4.1)\n1, 2, 3, 4\n’\n(b) The following new entry is inserted after code P502:\n‘\nP503\nRefer to manufacturer/ supplier/… for information on disposal/recovery/ recycling\nExplosives (section 2.1)\nUnstable explosives and Divisions 1.1, 1.2, 1.3, 1.4, 1.5\n… Manufacturer/supplier to specify appropriate source of information in accordance with local/regional/national/international regulations as applicable.\n’\n(7) Table 1.2 is amended as follows:\n(a) The following new entry is inserted:\n‘\nP212\nLanguage\nBG\nДа се избягва нагряване в затворено пространство или понижаване на съдържанието на десенсибилизиращия агент.\nES\nEvitar el calentamiento en condiciones de aislamiento o la reducción del agente insensibilizante.\nCS\nZamezte zahřívání v uzavřeném obalu nebo snížení objemu znecitlivujícího prostředku.\nDA\nUndgå opvarmning under indeslutning eller reduktion af det desensibiliserende middel.\"\nDE\nErhitzen unter Einschluss und Reduzierung des Desensibilisierungsmittels vermeiden.\nET\nVältida suletuna kuumutamist ja desensibilisaatori vähenemist.\nEL\nΝα αποφεύγεται η θέρμανση σε περιορισμένο χώρο και η μείωση του παράγοντα απευαισθητοποίησης.\nEN\nAvoid heating under confinement or reduction of the desensitising agent.\nFR\nÉviter d'échauffer en milieu confiné ou en cas de diminution de la quantité d'agent désensibilisateur.\nGA\nSeachain an téamh i limistéar iata nó i gcás laghdú ar an dí-íogróir.\nHR\nIzbjegavati zagrijavanje u zatvorenom prostoru ili smanjenje udjela desenzitirajućeg agensa.\nIT\nEvitare di riscaldare sotto confinamento o di ridurre l'agente desensibilizzante.\nLV\nNepieļaut karsēšanu slēgtā vidē vai desensibilizējošā aģenta daudzuma samazināšanos.”\nLT\nVengti kaitimo uždaroje talpykloje arba desensibilizacijos veiksnio poveikio sumažėjimo.\nHU\nKerülje a hevítést zárt térben vagy a deszenzibilizáló szer mennyiségének csökkenése esetén.\nMT\nEvita t-tisħin fil-magħluq jew it-tnaqqis tal-aġenti disensitizzanti.\nNL\nVermijd verwarming onder opsluiting of vermindering van de ongevoeligheidsagens.\nPL\nUnikać ogrzewania pod zamknięciem lub w sytuacji zmniejszonej zawartości środka odczulającego.”\nPT\nEvitar o aquecimento em ambiente fechado ou a redução do agente dessensibilizado.»\nRO\nA se evita încălzirea în mediu confinat sau în caz de scădere a agentului de desensibilizare\nSK\nZabráňte zahrievaniu v ohraničenom priestore alebo zníženiu obsahu desenzibilizačného činidla.\nSL\nIzogibati se segrevanju v zaprtem prostoru ali zmanjšanju vsebnosti desenzibilizatorja.“.\nFI\nVältettävä kuumentamista suljetussa astiassa tai flegmatointiaineen vähentämistä.\nSV\nUndvik uppvärmning i sluten behållare eller reducering av det okänsliggörande ämnet.\n’",
  "extent": "E+W+S+N.I.",
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/eur/2019/521/annex/IV",
    "retrieved_at": "2026-11-01T14:43:29.678232+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}