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Annex VI CRITERIA FOR VACCINES AGAINST INFECTION WITH NEWCASTLE DISEASE VIRUS

United Kingdom

Original text. Later amendments are not shown.

Live attenuated vaccines against infection with Newcastle disease virus must be prepared from a Newcastle disease virus strain for which the master seed has been tested and shown to have an intracerebral pathogenicity index (ICPI) of:

  1. (a)

    less than 0,4 if not less than 107 EID50 (50 % Embryo Infectious Dose) are administrated to each bird in the ICPI test; or

  2. (b)

    less than 0,5 if not less than 108 EID50 are administered to each bird in the ICPI test.