{
  "url": "https://openlegislation.uk/genetically-modified-organisms-contained-use-regulations-1992/schedule-2/paragraph-2",
  "json_url": "https://openlegislation.uk/genetically-modified-organisms-contained-use-regulations-1992/schedule-2/paragraph-2.json",
  "legislation": "uksi/1992/3217",
  "legislation_title": "The Genetically Modified Organisms (Contained Use) Regulations 1992",
  "legislation_url": "https://openlegislation.uk/genetically-modified-organisms-contained-use-regulations-1992",
  "path": "schedule/2/paragraph/2",
  "kind": "paragraph",
  "number": "2",
  "heading": "Vectors/Insert",
  "text": "(a) well characterised and free from known harmful sequences;\n(b) limited in size as much as possible to the genetic sequences required to perform the intended function;\n(c) should not increase the stability of the construct in the environment (unless that is a requirement of intended function);\n(d) should be poorly mobilisable;\n(e) should not transfer any resistance markers to micro-organisms not known to acquire them naturally (if such acquisition could compromise use of drugs to control disease agents).",
  "extent": null,
  "status": null,
  "version": "current",
  "annotations": [],
  "outstanding_effects": [
    {
      "type": "substituted",
      "affecting": "uksi/1996/967",
      "affecting_title": "The Genetically Modified Organisms (Contained Use) (Amendment) Regulations 1996"
    }
  ],
  "provenance": {
    "source": "legislation.gov.uk",
    "source_url": "https://www.legislation.gov.uk/uksi/1992/3217/schedule/2/paragraph/2",
    "retrieved_at": "2026-10-29T14:08:32.086650+00:00"
  },
  "licence": "Open Government Licence v3.0",
  "licence_url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/",
  "attribution": "Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives."
}