# The Genetically Modified Organisms (Contained Use) Regulations 1992, Paragraph 2: Vectors/Insert


(a) well characterised and free from known harmful sequences;
(b) limited in size as much as possible to the genetic sequences required to perform the intended function;
(c) should not increase the stability of the construct in the environment (unless that is a requirement of intended function);
(d) should be poorly mobilisable;
(e) should not transfer any resistance markers to micro-organisms not known to acquire them naturally (if such acquisition could compromise use of drugs to control disease agents).

---
Source: https://www.legislation.gov.uk/uksi/1992/3217/schedule/2/paragraph/2 (the official version)
Page: https://openlegislation.uk/genetically-modified-organisms-contained-use-regulations-1992/schedule-2/paragraph-2
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.