# The Medicines (Prohibition of Non-medicinal Antimicrobial Substances) Order 1977, Part II


Column 1
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Class of substance
Meaning
1. Amphotericins
1. Antimicrobial substances or mixtures of such substances produced by Streptomyces nodosus.
2. Cephalosporins
2. Antimicrobial substances containing in their chemical structure a fused dihydrothiazine β-lactam nucleus.
3. Gentamicins
3. Any antimicrobial basic substance or mixture of such substances produced by the strain Micromonospora purpurea which on 1st September 1967 was numbered NRRL 2953 in the culture collection of the Northern Utilisation Research and Development Branch of the United States Department of Agriculture.
4. Kanamycins
4. Any antimicrobial substance or mixture of such substances produced by Streptomyces Kanamyceticus.
5. Lincomycins
5. Antimicrobial substances produced by Streptomyces lincolnensis (var. lincolnensis). These substances are the basic amides of hygric acid or of a substituted hygric acid with 6-amino-6, 8-dideoxy-1-thiogalacto-octopyranose or with substituted 6-amino-6, 8-dideoxy-1-thiogalacto-octopyranose.
6. Neomycins
6. Antimicrobial substances or mixtures of such substances produced by Streptomyces fradiae which are complex organic bases and which yield on hydrolysis with mineral acids the base neamine.
7. Penicillins
7. Any antimicrobial acid which contains in its structure a fused thiazolidine β-lactam nucleus.
8. Polymixins
8. Any antimicrobial substance produced by any strain of Bacillus polymyxa.
9. Rifamycins
9. A group of related antimicrobial macrolactams produced by the growth of Streptomyces mediterranei and containing the chemical structure of 11-acetoxy-7,9, 15-trihydroxy-13-methoxy-2,6,8,10,12-pentamethylpentadeca-2,4, 14-trienoic acid amide attached by the nitrogen atom and by the oxygen atom in the 15-position respectively to the 7- and 2-positions of a 5,6, 9-trioxygenated 2, 4-dimethyl-1-oxonaptho (2, 1-b) furan.
10. Ristocetins
10. Antimicrobial substances produced by a strain of a Nocardia species referred to as Nocardia lurida.
11. Streptomycins
11. Any antimicrobial complex organic base or mixture of such bases produced by Streptomyces griseus which:—
(a) yields on hydrolysis with mineral acids the base streptidine (meso-1 3-diguanidocyclohexane-2,4,5,6-tetraol); and
(b) yields on hydrolysis by a 4 per cent solution of sodium hydroxide the substance maltol (3-hydroxy-2-methyl-8-pyrone).
12. Sulphanilamide
12. Sulphanilamide being p-aminobenzenesulphonamide, having any of the hydrogen atoms of either or both nitrogen atoms substituted by an equal number of univalent atoms or radicals.
13. Tetracyclines
13. Antimicrobial bases which contain the chemical structure naphthacene-2-carboxamide, hydrogenated to any extent and having each of the positions 1,3,10,11,12 and 12a substituted by a hydroxyl or an oxo group.

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Source: https://www.legislation.gov.uk/uksi/1977/2131/schedule/1/part/II (the official version)
Page: https://openlegislation.uk/medicines-prohibition-of-non-medicinal-antimicrobial-substances-order-1977/schedule-1/part-II
Contains public sector information licensed under the Open Government Licence v3.0. Source: legislation.gov.uk, The National Archives.