OpenLegislation

Annex F1

United Kingdom

Original text. Later amendments are not shown.

F2List of scheduled substances

Category 1
F3SubstanceCN designation(if different)CN Codef1 CAS Nof2
(1)

OJ No. L 290, 28.10.2002, p. 1.

(2)

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.

(3)

Also named (+)-norpseudoephedrine, CN code 2939 43 00, CAS No 492-39-7.

(4)

Also known as ethyl 3-oxo-2-phenylbutanoate, according to The International Union of Pure and Applied Chemistry (IUPAC).

(5)

Also known as methyl 2-(2H-1,3-benzodioxol-5-yl)-3-oxobutanoate, according to IUPAC.

(6)

And its ethyl, methyl (CAS No 80532-66-7), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as BMK glycidic acid.

(7)

And its ethyl (CAS No 28578-16-7), methyl (CAS No 13605-48-6), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as PMK glycidic acid.

(8)

Also known as 5-[2-(1,3-benzodioxol-5-yl)acetyl]–2,2-dimethyl–1,3-dioxane–4,6-dione, according to IUPAC.

1-Phenyl-2-propanonePhenylacetone2914 31 00103-79-7
Diethyl (phenylacetyl) propanedioate (also referred to as DEPAPD)2918 30 0020320-59-6
Methyl alpha-phenylacetoacetate (also referred to as MAPA)2918 30 0016648-44-5
Ethyl alpha-phenylacetoacetate (also referred to as EAPA) f3Ex 2918 30 005413-05-8
2-methyl-3-phenyloxirane-2-carboxylic acid (also referred to as BMK glycidic acid) f42918 99 9025547-51-7
N-acetylanthranilic acid2-Acetamidobenzoic acid2924 23 0089-52-1
Alpha-phenylacetoacetamide (also referred to as APAA)2924 29 704433-77-6
Alpha-phenylacetoacetonitrile (also referred to as APAAN)2926 40 004468-48-8
Isosafrol (cis+trans)2932 91 00120-58-1
3,4-Methylenedioxyphenylpropan-2-one1-(1,3-Benzodioxol-5-yl)propan-2-one2932 92 004676-39-5
Piperonal2932 93 00120-57-0
Safrole2932 94 0094-59-7
Methyl 3-oxo-2-(3,4-methylenedioxyphenyl)butanoate (also referred to as MAMDPA) f5Methyl 3-oxo-2-(3,4-methylenedioxyphenyl)butanoateEx 2932 99 001369021-80-6
3-(1,3-benzodioxol-5-yl)-2-methyl-oxirane-2-carboxylic acid (also referred to as PMK glycidic acid) f62932 99 002167189-50-4
Isopropylidene (2-(3,4-methylenedioxyphenyl)acetyl)malonate (also referred to as IMDPAM) f7IMDPAM2932 99 00
N-phenyl-1-(2-phenylethyl)piperidin-4-amine4-anilino-N- phenethylpiperidine (ANPP)2933 36 0021409-26-7
1-(2-phenylethyl)piperidin-4-oneN-phenethyl-4-piperidone (NPP)2933 37 0039742-60-4
N-phenylpiperidin-4-amine (also referred to as 4-AP)2933 39 9923056-29-3
Tert-butyl 4-anilinopiperidine-1-carboxylate (also referred to as 1-boc-4-AP)2933 39 99125541-22-2
N-phenyl-N-(piperidin-4-yl)propanamide (also referred to as norfentanyl)2933 39 991609-66-1
4-piperidonePiperidin-4-one2933 39 9941661-47-6
1-boc-4-piperidonetert-butyl 4-oxopiperidine-1-carboxylate2933 39 9979099-07-3
Ephedrine2939 41 00299-42-3
Pseudoephedrine2939 42 0090-82-4
Norephedrine2939 44 0014838-15-4
Ergometrine2939 61 0060-79-7
Ergotamine2939 62 00113-15-5
Lysergic acid2939 63 0082-58-6
(1R,2S)-(-)-chloroephedrine2939 79 90110925-64-9
(1S,2R)-(+)-chloroephedrine2939 79 901384199-95-4
(1S,2S)-(+)-chloropseudoephedrine2939 79 9073393-61-0
(1R,2R)-(-)-chloropseudoephedrine2939 79 90771434-80-1
The stereoisomeric forms of the substances listed in this Category not being cathinef8 whenever the existence of such forms is possible.
The salts of the substances listed in this Category whenever the existence of such salts is possible and not being the salts of cathine.
Category 2
F4Substance CN designation (if different) CN Code f9 CAS No f10
(1)

OJ No. L 290, 28.10.2002, p. 1.

(2)

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.

Red phosphorus2804 70 107723-14-0
Acetic anhydride2915 24 00108-24-7
Phenylacetic acid2916 34 00103-82-2
Anthranilic acid2922 43 00118-92-3
Piperidine2933 32 00110-89-4
Potassium permanganate2841 61 007722-64-7
The salts of the substances listed in this Category whenever the existence of such salts is possible.
Category 3

OJ L 290, 28.10.2002, p. 1.

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. It must be understood that the CAS Nos for the salts of the substances listed above will be different from those given.

SubstanceCN designation(if different)CN Codef11 CAS Nof12
Hydrochloric acidHydrogen chloride2806 10 007647-01-0
Sulphuric acidF52807 00 007664-93-9
Toluene2902 30 00108-88-3
Ethyl etherDiethyl ether2909 11 0060-29-7
Acetone2914 11 0067-64-1
MethylethylketoneButanone2914 12 0078-93-3
The salts of the substances listed in this Category whenever the existence of such salts is possible and not being the salts of hydrochloric acid and sulphuric acid.
F6Category 4
Substance CN designation (if different) CN Code
Medicinal products and veterinary medicinal products containing ephedrine or its salts Containing ephedrine or its salts

F73003 41 00

F83004 41 00

Medicinal products and veterinary medicinal products containing pseudo-ephedrine or its salts Containing pseudoephedrine (INN) or its salts

F93003 42 00

F103004 42 00

Annotations

Textual amendments

F1

Regulation revoked (N.I.) (29.6.2026) by The Controlled Drugs (Drug Precursors) (Amendment and Revocation) Regulations 2026 (S.I. 2026/607), reg. 1(1), Sch.

F2

Substituted by Regulation (EU) No 1259/2013 of the European Parliament and of the Council of 20 November 2013 amending Council Regulation (EC) No 111/2005 laying down rules for the monitoring of trade between the Community and third countries in drug precursors.

F3

Annex Table substituted (E.W.S.) (29.6.2026) by The Controlled Drugs (Drug Precursors) (Amendment and Revocation) Regulations 2026 (S.I. 2026/607), regs. 1(1), 6(24)(a)

F4

Annex Table substituted (29.6.2026) by The Controlled Drugs (Drug Precursors) (Amendment and Revocation) Regulations 2026 (S.I. 2026/607), regs. 1(1), 6(24)(b)

F5

Substituted by Commission Delegated Regulation (EU) 2020/1737 of 14 July 2020 amending Regulation (EC) No 273/2004 of the European Parliament and of the Council and Council Regulation (EC) No 111/2005 as regards the inclusion of certain drug precursors in the list of scheduled substances (Text with EEA relevance).

F6

Inserted by Regulation (EU) No 1259/2013 of the European Parliament and of the Council of 20 November 2013 amending Council Regulation (EC) No 111/2005 laying down rules for the monitoring of trade between the Community and third countries in drug precursors.

F7

Substituted by Commission Delegated Regulation (EU) 2020/1737 of 14 July 2020 amending Regulation (EC) No 273/2004 of the European Parliament and of the Council and Council Regulation (EC) No 111/2005 as regards the inclusion of certain drug precursors in the list of scheduled substances (Text with EEA relevance).

F8

Substituted by Commission Delegated Regulation (EU) 2020/1737 of 14 July 2020 amending Regulation (EC) No 273/2004 of the European Parliament and of the Council and Council Regulation (EC) No 111/2005 as regards the inclusion of certain drug precursors in the list of scheduled substances (Text with EEA relevance).

F9

Substituted by Commission Delegated Regulation (EU) 2020/1737 of 14 July 2020 amending Regulation (EC) No 273/2004 of the European Parliament and of the Council and Council Regulation (EC) No 111/2005 as regards the inclusion of certain drug precursors in the list of scheduled substances (Text with EEA relevance).

F10

Substituted by Commission Delegated Regulation (EU) 2020/1737 of 14 July 2020 amending Regulation (EC) No 273/2004 of the European Parliament and of the Council and Council Regulation (EC) No 111/2005 as regards the inclusion of certain drug precursors in the list of scheduled substances (Text with EEA relevance).

Footnotes

f1

(1)

OJ No. L 290, 28.10.2002, p. 1.

f2

(2)

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.

f3

(4)

Also known as ethyl 3-oxo-2-phenylbutanoate, according to The International Union of Pure and Applied Chemistry (IUPAC).

f4

(6)

And its ethyl, methyl (CAS No 80532-66-7), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as BMK glycidic acid.

f5

(5)

Also known as methyl 2-(2H-1,3-benzodioxol-5-yl)-3-oxobutanoate, according to IUPAC.

f6

(7)

And its ethyl (CAS No 28578-16-7), methyl (CAS No 13605-48-6), propyl, isopropyl, butyl, isobutyl, sec-butyl and tert-butyl esters, with the same CN code as PMK glycidic acid.

f7

(8)

Also known as 5-[2-(1,3-benzodioxol-5-yl)acetyl]–2,2-dimethyl–1,3-dioxane–4,6-dione, according to IUPAC.

f8

(3)

Also named (+)-norpseudoephedrine, CN code 2939 43 00, CAS No 492-39-7.

f9

(1)

OJ No. L 290, 28.10.2002, p. 1.

f10

(2)

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. The CAS Nos for the salts of the substances listed above will be different from those given.

f11

OJ L 290, 28.10.2002, p. 1.

f12

The CAS No is the ‘Chemical abstracts service registry number’, which is a unique numeric identifier specific to each substance and its structure. The CAS No is specific to each isomer and to each salt of each isomer. It must be understood that the CAS Nos for the salts of the substances listed above will be different from those given.