Division 1.0.2 The human health hazard assessment shall consider the toxicokinetic profile (i.e. absorption, metabolism, distribution and elimination) of the substance and the following groups of effects:X1F1

1. (1)

   acute effects such as acute toxicity, irritation and corrosivity;

2. (2)

   sensitisation;

3. (3)

   repeated dose toxicity; and

4. (4)

   CMR effects (carcinogenity, germ cell mutagenicity and toxicity for reproduction).

Based on all the available information, other effects shall be considered when necessary.