Division 3.5.1.3 F1

The more general terms ‘ genotoxic ’ and ‘ genotoxicity ’ apply to agents or processes which alter the structure, information content, or segregation of DNA, including those which cause DNA damage by interfering with normal replication processes, or which in a non- physiological manner (temporarily) alter its replication. Genotoxicity test results are usually taken as indicators for mutagenic effects.