Division 2.2.1.3

The mode of action of the micro-organism shall be evaluated in as much detail as appropriate. The possible role of metabolites/toxins for the mode of action shall be evaluated and when identified, the minimal effective concentration for each active metabolite/toxin shall be established. Information on mode of action can be a very valuable tool in identifying potential risks. Aspects to be considered in the evaluation, are:

1. (a)

   antibiosis;

2. (b)

   induction of plant resistance;

3. (c)

   interference with the virulence of a pathogenic target organism;

4. (d)

   endophytic growth;

5. (e)

   root colonisation;

6. (f)

   competition of ecological niche (e.g. nutrients, habitats);

7. (g)

   parasitisation;

8. (h)

   invertebrate pathogenicity.