OpenLegislation

Division NEO-CSEP: Clinical Sepsis

United Kingdom

Original text. Later amendments are not shown.

ALL of the 3 following criteria:

  • Supervising physician started appropriate antimicrobial therapy for sepsis for at least five days.

  • No detection of pathogens in blood culture or not tested

  • No obvious infection at another site

AND two of the following criteria (without other apparent cause):

  • Fever (> 38 °C) or temperature instability (frequent post-set of the incubator) or hypothermia (< 36,5 °C)

  • Tachycardia (> 200/min) or new/increased bradycardia (< 80/min)

  • Capillary refilling time (CRT) > 2 s

  • New or increased apnoea (s) (> 20 s)

  • Unexplained metabolic acidosis

  • New-onset hyperglycaemia (> 140 mg/dl)

  • Another sign of sepsis (skin colour (only if the CRT is not used), laboratory signs (CRP, interleukin), increased oxygen requirement (intubation), unstable general condition of the patient, apathy)