Division 1.3.3.4 Observations

Clinical observations

Animals should be carefully observed once daily for any clinical signs, either of local irritation at the application site or of systemic toxicity. All observations are systematically recorded with individual records being maintained for each animal.

Body Weights

As stated in section 1.3.3.1, individual animal body weights should be measured at the start of the test and at the scheduled kill of the animals.