Division 3.2.2.7 Determination of No Observed Adverse Effect Levels (NOAEL)
United Kingdom
The NOAEL is generally based on toxicological effects, but pharmacological effects might occasionally be more appropriate.
The lowest NOAEL shall be selected. All findings from previous sections together with all other relevant published data (including any relevant information on the effects of the active substance on human) and information, where appropriate, on chemicals having a closely related chemical structure shall be taken into consideration in identifying the lowest NOAEL, expressed as mg per kg body weight per day.
Notes on Division 3.2.2
Textual amendments
- F1
Words in Annex 2 point 3.2.2 substituted (31.12.2020) by The Animal Feed (Amendment) (EU Exit) Regulations 2019 (S.I. 2019/654), regs. 1, 83(d)(ii); 2020 c. 1, Sch. 5 para. 1(1)
- F2
Word in Annex 2 s. 3 point 3.2.2 substituted (27.2.2025) by The Retained EU Law (Revocation and Reform) Act 2023 (Consequential Amendments) Regulations 2025 (S.I. 2025/82), reg. 1(2), Sch. 11 para. 11(d)(ii)